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NMDA receptor antagonists are a class of psychoactive substances that work by antagonizing, or inhibiting the action of, the NMDA receptor (NMDAR). The NMDA receptor is one of the receptor types for glutamate which is one of the principal excitatory neurotransmitters and is involved in cognitive functions such as learning and memory.What are some NMDA agonists?
NMDA Agonists. Prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels; important in long-term potentiation, ischemia, and epilepsy. N-Methyl-D-aspartic acid (NMDA) plays a crucial role in release of luteinizing hormone and PRL (prolactin) in the pituitary gland and GnRH (gonadotropin releasing hormone) in the hypothalamus.What triggers anti NMDA receptor encephalitis?
Anti-NMDA receptor encephalitis is a disease occurring when antibodies produced by the body’s own immune system attack NMDA receptors in the brain.Does anti-NMDA receptor encephalitis have a cure?
Fast Treatment Can Reverse Anti-NMDA-Receptor Encephalitis. The researchers suggest that these antibodies reduced the numbers of cell-surface NMDA receptors and receptor clusters in the postsynaptic dendrites of the nervous system. This effect, they say, could be reversed by removing the antibodies.