What is the hardest thing to make in little alchemy? The rarest item in Little Alchemy is The Doctor. The Doctor requires 27 combinations to make, starting with Earth and Fire and eventually getting to Life, Moon, Human, and Time.How do you make people in Little alchemy?
Article SummaryX. To make life in little Little Alchemy, start by dragging some air onto the playing board. Then, place some fire on top of the air to create energy. Once you've created energy, combine some earth and water on the board to create mud.