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Other research focuses on the causes and pathophysiology of Down syndrome. The IDDB supports a broad range of activities in this area, including explorations of the signaling pathways, metabolic processes, and mitochondrial functions that affect the development of people with Down syndrome.What is the current research on Down syndrome?
Scientists conducting research on Down syndrome have developed a mouse model to analyze the developmental consequences of the disorder. Mice are used because a large stretch of mouse chromosome 16 has many genes in common with those on human chromosome 21.What are the results of Down syndrome?
People with Down syndrome often experience a gradual decline in thinking ability (cognition) as they age, usually starting around age 50. Down syndrome is also associated with an increased risk of developing Alzheimer disease, a brain disorder that results in a gradual loss of memory, judgment, and ability to function.Why is research for people with Down syndrome important?
Research is important for people with Down syndrome, especially since Down syndrome is the least funded genetic condition by the National Institutes of Health (NIH). The funding for Down syndrome research at the NIH started a continual and precipitous decline in the year 2001.