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Reference ID: 3237516 - Food and Drug Administration
Because of high plasma protein binding, apixaban is not expected to be dialyzable [see Clinical Pharmacology (12.3)]. Protamine sulfate and vitamin K would not be expected to affect the anticoagulant activity of apixaban. There is no experience with antifibrinolytic agents (tranexamic acid, aminocaproic acid) in individuals receiving apixaban.
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How to Convert Between Anticoagulants - Pharmacy Times
Jan 26, 2015 · Pradaxa package insert. Eliquis package insert. Xarelto package insert. Alberts MJ, Eikelboom JW, Hankey GJ. Antithrombotic therapy for stroke prevention in non-valvular atrial fibrillation. Lancet Neurology. 2012;11:1066—81. Schulman S, Crowther MA. How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch.
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Eliquis (apixaban): Basics, Side Effects & Reviews - GoodRx
Typical dosing for Eliquis (apixaban) Nonvalvular atrial fibrillation: The dose of Eliquis (apixaban) is usually 5 mg by mouth twice daily. There are some people who will only take 2.5 mg by mouth twice daily. Blood clot prevention after surgery: The dose of Eliquis (apixaban) is usually 2.5 mg by mouth twice daily. Blood clot and pulmonary embolism treatment: The dose …
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UW Medicine Monitoring for Antithrombotic Agents
For apixaban, no “therapeutic range” has been established. Observed peak and trough concentrations patients exposed to therapeutic dosing are described below* ... as noted in package insert (2) range of concentration values from these trials (data on file, GSK)
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Apixaban for End-Stage Kidney Disease | Circulation
Oct 08, 2018 · Randomized trials to date of apixaban versus warfarin for AF excluded patients with severe and end-stage kidney disease, calculated creatinine clearance <25 mL per minute. 4,5 The US Food and Drug Administration cautiously extended apixaban use to patients with end-stage kidney disease on hemodialysis based on limited pharmacokinetic data. 6 ...
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Dilantin: Package Insert / Prescribing Information - Drugs.com
Mar 01, 2022 · Package insert / prescribing information Generic name: phenytoin sodium Dosage form ... Individual drug package inserts should be consulted. The addition or withdrawal of phenytoin during concomitant therapy with these agents may require adjustment of the dose of these agents to achieve optimal clinical outcome. ... Apixaban, dabigatran ...
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Enoxaparin Sodium Injection: Package Insert / Prescribing …
Dec 01, 2021 · Package insert / prescribing information Dosage form: injection Drug class: Heparins. ... Package Factor: 71288-426-03: ... Apixaban Noninferior to Enoxaparin for Postoperative VTE Prophylaxis Drugs.com Mobile Apps. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. ...
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Prophylaxis of DVT following hip or knee replacement surgery …
ELIQUIS® (apixaban) tablets, for oral use Initial U.S. Approval: 2012 WARNING: (A) PREMATURE DISCONTINUATION OF ELIQUIS INCREASES THE RISK OF THROMBOTIC EVENTS (B) SPINAL/EPIDURAL HEMATOMA See full prescribing information for complete boxed warning. (A) PREMATURE DISCONTINUATION OF ELIQUIS INCREASES THE RISK OF
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ANDEXXA | FDA - U.S. Food and Drug Administration
May 26, 2022 · Indicated for patients treated with rivaroxaban and apixaban, when reversal of anticoagulation is needed due to life-theratening or uncontrolled bleeding; Product Information. Package Insert - ANDEXXA
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