|apixaban vs rivaroxaban||0.55||0.7||133||56|
|apixaban vitamin k||1.3||0.3||6327||73|
|apixaban vs warfarin||0.63||0.5||5066||3|
|apixaban icd 10||0.91||0.4||6961||90|
|apixaban via peg tube||1.34||0.8||6407||72|
|apixaban vs eliquis||0.69||0.4||423||48|
|apixaban vs xarelto||0.38||0.4||2397||69|
|apixaban via de administracion||1.09||0.1||5171||60|
|apixaban vs edoxaban||0.41||0.1||8047||23|
|apixaban vitamin k antagonist||1.77||0.7||8130||20|
|apixaban rivaroxaban dabigatran||1.79||0.3||1017||53|
|apixaban and ivc filter||0.77||0.1||5123||82|
|ivc and apixaban||0.05||1||8456||62|
|ivc ligation apixaban||1.57||0.9||7937||41|
What is apixaban? Apixaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. Apixaban is also used after hip or knee replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).What anticoagulants should be given with apixaban?
b) Begin both a parenteral anticoagulant (LMWH/fondaparinux or UFH) and warfarin at the same time that the next dose of apixaban would have been givenWhen should apixaban be taken with CYP3A4 inhibitors?
If taking apixaban dose >2.5 mg BID, decrease dose by 50% if coadministered with strong dual inhibitors of CYP3A4 and P-gp; if currently taking apixaban 2.5 mg PO BID, avoid coadministration with strong dual inhibitors of CYP3A4 and P-gpWhat is the highest dose of apixaban?
The dose-proportionality analysis showed that apixaban exposure increased proportionally to dose across the approved dose range (2.5–10 mg) . Exposure was less than proportional for doses greater than 10 mg; this appeared to be driven by the less-than-proportional increases in exposure following administration of the 25- and 50-mg doses.