Keyword Analysis & Research: apixaban esrd

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Frequently Asked Questions

Is apixaban safe for ESRD patients on dialysis?

No dosage adjustment for apixaban is recommended for patients with ESRD on dialysis. Inform patients with AF and ESRD on dialysis that results of a new study suggest that apixaban is a safe and effective treatment option compared with warfarin.

What is the role of apixaban (Eliquis) in patients with CKD 5?

Although apixaban (Eliquis) is approved for use in patients with CKD for venous thrombosis (VTE), its role in patients with CKD 5 and on dialysis is less defined.

What is apixaban renal dose adjustment based on?

Apixaban Renal Dose Adjustment Most renal dosing recommendations are based on calculated CrCl using the Cockcroft-Gault formula, and limited drugs utilize eGFR for dosing. Interestingly, the apixaban renal dose adjustment recommendation is based on SCr, and is the only drug on the market with such dose adjustment criteria.

Is apixaban an effective nonvitamin K anticoagulant?

Background: At the present, apixaban is the only nonvitamin K oral anticoagulant approved by the Food and Drug Administration for use with patients with creatinine clearance <15 mL/min or end-stage renal disease (ESRD).

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