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Apixaban - Wikipedia
Apixaban, sold under the brand name Eliquis, ... Full dose apixaban (5 mg bid) can be used, unless at least two of the following characteristics apply: patient age is 80 years or older, body weight is 60 kg or less, and serum creatinine is 1.5 mg/dL or higher, in which case dose reduction to 2.5 mg bid is indicated. ...
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Validity of different dose reduction criteria for apixaban
Reduced-dose apixaban is recommended in patients fulfilling 2 of 3 criteria: age ≥80 years, body weight ≤60 kg, and serum creatinine ≥1.5 mg/dL. However, patient weight is often not available in electronic health data. We examined the validity of alternative definitions based …
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Apixaban (Oral Route) Side Effects - Mayo Clinic
Jul 29, 2006 · Apixaban is used to treat or prevent deep venous thrombosis, a condition in which harmful blood clots form in the blood vessels of the legs. These blood clots can travel to the lungs and can become lodged in the blood vessels of the lungs, causing a condition called pulmonary embolism. ... The dose of this medicine will be different for ...
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Apixaban | Drugs | BNF | NICE
Anaesthesia with postoperative indwelling epidural catheter (risk of paralysis—monitor neurological signs and wait 20–30 hours after apixaban dose before removing catheter and do not give next dose until at least 5 hours after catheter removal); elderly; low body-weight; risk of …
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Outcomes Associated With Apixaban Use in Patients With End ... - PubMed
Oct 09, 2018 · Among patients with ESKD and AF on dialysis, apixaban use may be associated with a lower risk of major bleeding compared with warfarin, with a standard 5 mg twice a day dose also associated with reductions in thromboembolic and mortality risk.
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Apixaban (Oral Route) Description and Brand Names - Mayo Clinic
Apixaban is also used to prevent stroke and blood clots in patients with certain heart rhythm problem (eg, nonvalvular atrial fibrillation). Apixaban is a factor Xa inhibitor, an anticoagulant. It works by decreasing the clotting ability of the blood and helps preventing harmful clots from forming in the blood vessels.
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Deep Venous Thrombosis and Pulmonary Embolism: Current …
Discontinue apixaban and begin the new anticoagulant when the next dose of apixaban is due. Dabigatran (Pradaxa): 150 mg twice per day after 5 to 10 days of parenteral anticoagulation.
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Apixaban (Eliquis) | Davis’s Drug Guide
When converting from warfarin , discontinue warfarin and start apixaban when INR is <2.0.; When converting from apixaban to warfarin , apixaban affects INR, so INR measurements may not be useful for determining appropriate dose of warfarin.If continuous anticoagulation is necessary, discontinue apixaban and begin both a parenteral anticoagulant and warfarin at …
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Eliquis: Uses, Dosage & Side Effects Information - Drugs.com
Oct 19, 2021 · Eliquis (apixaban) is used to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Includes Eliquis side effects, interactions and indications. ... Your doctor may occasionally change your dose. You may take Eliquis with or without food. If you cannot swallow a tablet whole, crush it and mix with ...
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Decadron, Dexamethasone Intensol (dexamethasone) dosing, …
apixaban. dexamethasone will decrease the level or effect of apixaban by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. ... Dose reduction may be needed for coadministered drugs that are predominantly metabolized by CYP3A. crizotinib increases levels of dexamethasone by P-glycoprotein (MDR1) efflux transporter. Use ...
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