The production process of adalimumab is complex and it is based in the called p … Adalimumab is a fully human monoclonal antibody targeted toward tumor necrosis factor alpha (TNF-alpha).What type of antibody is adalimumab?
HUMIRA (adalimumab) is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF). HUMIRA was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1: k constant regions.What is adadalimumab?
Adalimumab was the first fully human monoclonal antibody approved by the US Food and Drug Administration (FDA). It was derived from phage display.Does adalimumab increase or decrease CRP production?
Usage of adalimumab leads to a decrease in CRP production. Therefore, the relationship between adalimumab and CRP was described using an indirect response model with inhibition of CRP input (Figure 1), as in previous studies 17,22,23.