Keyword Analysis & Research: adalimumab epitope

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What is the mechanism of action of adalimumab?

Adalimumab is a TNF-inhibiting, anti-inflammatory, biologic medication. It binds to tumor necrosis factor-alpha (TNFα), which normally binds to TNFα receptors, leading to the inflammatory response of autoimmune diseases.

How effective is adalimumab for the treatment of ulcerative colitis?

Adalimumab may be effective and well tolerated in ulcerative colitis. It has been approved by the U.S. Food and Drug Administration (FDA) for treatment of moderate to severe cases in adults.

When was adalimumab approved for medical use?

Adalimumab was approved for medical use in the United States in 2002. It is on the World Health Organization's List of Essential Medicines, which lists the safest and most effective medicines needed in a health system.

Is adalimumab approved for psoriatic arthritis?

As of 2008, adalimumab had been approved by the FDA for the treatment of rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, moderate to severe chronic psoriasis and juvenile idiopathic arthritis.

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